![]() These protective effects may be attributed to their anti-inflammatory properties by attenuating serum C-reactive protein levels and antioxidant effects by reducing lipid peroxidation marker, malondialdehyde levels, and increasing renal superoxide dismutase activity. Ginger and Arabic Gum showed renoprotective effects in renal failure. This effect was improved by a treatment with 1% dietary ginger 1 month in rats which suggest that ginger may have protective role against the ethanol induced hepatotoxicity. In vitro, zingerone scavenged O 2- and OH and suppressed lipid peroxidation, so it can possibly value in treatment of Parkinson's disease.Įthanol significantly decreased the superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and glutathione content in the hepatic tissue. Concomitant dietary feeding of ginger (1%w/w) significantly attenuated lindane-induced lipid peroxidation, reduced glutathione (GSH), and the GSH-dependent enzymes glutathione peroxidase, glutathione reductase, and glutathione S-transferase. Furthermore, feeding ginger to rats at 1% w/w during administration of malathion (20 ppm) for 4 weeks significantly attenuated malathion-induced lipid peroxidation. ![]() Animal modeling showed that ginger significantly lowered induced lipid peroxidation and raised the levels of antioxidant enzymes, together with serum glutathione. 6-Shogaol has exhibited the most potent antioxidant and anti-inflammatory properties in ginger, which can be attributed to the presence of alpha, beta-unsaturated ketone moiety. Strengthening the body's defenses by improving the antioxidant status will undoubtedly protect human against many chronic diseases. The anti-oxidative properties of ginger and its components have been explored in various in vitro and in vivo tests. In such circumstances of imbalance, extra antioxidant supplementation through dietary modules is essential for organism vitality. Increased production of free radicals results in oxidative stress that can lead to DNA damage. For the purpose of energy production, some free radicals which generated during the process of oxidation are essential. The rich phytochemistry of ginger includes components that scavenge free radicals produced in biological systems. This study aimed to review the current evidence on ginger effects as an anti-inflammatory and anti-oxidative. This effect may be due to anti-inflammatory effect of ginger and further investigation need to prove it in human. Ginger consumption before exercise might reduce naturally occurring quadriceps muscle pain during moderate-intensity cycling exercise. ![]() Inflammatory disorders such as gastritis, esophagitis, and hepatitis, which are caused not only by infectious agents such as viruses, bacteria, and parasites but also by physical and chemical agents like heat, acid, cigarette smoke, and foreign bodies, are recognized as risk factors for human cancer. The bioactive molecules of ginger like gingerols have shown antioxidant activity in various modules. Generation of free radicals or reactive oxygen species (ROS) during metabolism beyond the antioxidant capacity of a biological system results in oxidative stress, which plays an essential role in heart diseases, neurodegenerative diseases, cancer, and in the aging process. Furthermore, it has antimicrobial potential as well which can help in treating infectious diseases. It also has anti-inflammatory and anti-oxidative properties for controlling the process of aging. Ginger has staring potential for treating a number of ailments including degenerative disorders (arthritis and rheumatism), digestive health (indigestion, constipation and ulcer), cardiovascular disorders (atherosclerosis and hypertension), vomiting, diabetes mellitus, and cancer. ![]() On the contrary, non-volatile pungent compounds include gingerols, shogaols, paradols, and zingerone. Volatiles include sesquiterpene and monoterpenoid hydrocarbons providing the distinct aroma and taste of ginger. grouped fresh ginger into two wide range categories, i.e. The health-promoting perspective of ginger is attributed to its rich phytochemistry. Besides this, the rhizome of ginger has also been used in traditional herbal medicine. It originated in South-East Asia and then used in many countries as a spice and condiment to add flavor to food. Ginger (Zingiber officinale Rosc.) belongs to the family Zingiberaceae. ![]()
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